Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

4. Protein Structure

Peptide Bond

Biochemistry

4. Protein Structure

Peptide Bond

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Multiple Choice

During the process of translation, when is a peptide bond formed between amino acids?

When the ribosome binds to the mRNA at the start codon

When the release factor binds to the stop codon in the A site

When the aminoacyl-tRNA in the A site reacts with the growing polypeptide chain attached to the tRNA in the P site

When the tRNA exits the E site of the ribosome

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Verified step by step guidance

Understand the process of translation: Translation is the process by which the ribosome synthesizes a polypeptide chain using the mRNA sequence as a template. It involves three main stages: initiation, elongation, and termination.

Focus on the elongation phase: During elongation, amino acids are added one by one to the growing polypeptide chain. This process involves the A (aminoacyl), P (peptidyl), and E (exit) sites of the ribosome.

Identify the role of the A and P sites: The A site holds the incoming aminoacyl-tRNA, which carries the next amino acid to be added. The P site holds the tRNA that is attached to the growing polypeptide chain.

Explain peptide bond formation: A peptide bond is formed when the amino group of the amino acid on the tRNA in the A site reacts with the carboxyl group of the growing polypeptide chain attached to the tRNA in the P site. This reaction is catalyzed by the ribosome's peptidyl transferase activity.

Clarify the correct answer: The peptide bond formation occurs specifically when the aminoacyl-tRNA in the A site reacts with the growing polypeptide chain attached to the tRNA in the P site. This is a key step in the elongation phase of translation.