Multiple Choice
In a typical human cell, where does glycolysis occur?
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Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Glycolysis 1
Multiple Choice
During glycolysis, one glucose molecule is cleaved into two three-carbon molecules. What are these two molecules immediately after the aldolase reaction?
A
Two molecules of fructose 1,6-bisphosphate
B
One molecule of glyceraldehyde-3-phosphate (G3P) and one molecule of dihydroxyacetone phosphate (DHAP)
C
Two molecules of glyceraldehyde-3-phosphate (G3P)
D
Two molecules of pyruvate
Verified step by step guidance1
Recall the sequence of reactions in glycolysis leading up to the aldolase step: glucose is first phosphorylated and rearranged to fructose 1,6-bisphosphate.
Understand that the aldolase enzyme catalyzes the cleavage of fructose 1,6-bisphosphate, a six-carbon sugar, into two three-carbon molecules.
Identify the two three-carbon products formed immediately after the aldolase reaction: one molecule is glyceraldehyde-3-phosphate (G3P), and the other is dihydroxyacetone phosphate (DHAP).
Recognize that although DHAP is not directly used in the subsequent steps of glycolysis, it can be converted into G3P by the enzyme triose phosphate isomerase, allowing glycolysis to continue with two molecules of G3P.
Summarize that the aldolase reaction splits fructose 1,6-bisphosphate into one molecule of G3P and one molecule of DHAP, which are the immediate products of this step.
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