Multiple Choice
In cellular metabolism, what is the main purpose of glycolysis?
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Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Glycolysis 1
Multiple Choice
In glycolysis (from one molecule of glucose to two molecules of pyruvate), what is the net gain of ATP per glucose molecule under aerobic conditions?
A
0 ATP
B
6 ATP
C
2 ATP
D
4 ATP
Verified step by step guidance1
Understand the overall process of glycolysis: one molecule of glucose (6 carbons) is converted into two molecules of pyruvate (3 carbons each).
Identify the ATP investment phase: during the initial steps of glycolysis, 2 ATP molecules are consumed to phosphorylate glucose and its intermediates.
Identify the ATP payoff phase: later steps in glycolysis produce 4 ATP molecules by substrate-level phosphorylation (2 ATP per each pyruvate formed, and since 2 pyruvates are formed, total 4 ATP).
Calculate the net ATP gain by subtracting the ATP invested from the ATP produced: Net ATP = ATP produced - ATP consumed.
Conclude that the net gain of ATP per glucose molecule in glycolysis is 2 ATP under aerobic conditions.
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