Multiple Choice
In glycolysis, is NADH a substrate (reactant) or a product, and at which step is it formed?
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Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Glycolysis 1
Multiple Choice
Which of the following molecules is a net product of glycolysis (per glucose molecule) under aerobic conditions?
A
Acetyl-CoA
B
Pyruvate
C
Citrate
D
Oxaloacetate
Verified step by step guidance1
Step 1: Understand the overall process of glycolysis. Glycolysis is the metabolic pathway that converts one molecule of glucose (a 6-carbon sugar) into two molecules of pyruvate (each with 3 carbons), producing ATP and NADH in the process.
Step 2: Identify the net products of glycolysis per glucose molecule. Since one glucose molecule is split into two 3-carbon molecules, the main net products are 2 molecules of pyruvate, along with ATP and NADH.
Step 3: Recognize that Acetyl-CoA is not a direct product of glycolysis. Instead, pyruvate is converted into Acetyl-CoA in the mitochondria during the link reaction (pyruvate oxidation), which occurs after glycolysis under aerobic conditions.
Step 4: Understand that citrate and oxaloacetate are intermediates in the citric acid cycle (Krebs cycle), which takes place after glycolysis and pyruvate oxidation, not during glycolysis itself.
Step 5: Conclude that the net product of glycolysis per glucose molecule under aerobic conditions is pyruvate, as it is the direct output of the glycolytic pathway before entering further aerobic metabolism.
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