Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

8. Protein Function

Hemoglobin Cooperativity

Biochemistry

8. Protein Function

Hemoglobin Cooperativity

Previous problemNext problem

Struggling with Biochemistry?

Join thousands of students who trust us to help them ace their exams!Watch the first video

Multiple Choice

Which of the following statements best describes the effect of increased temperature on oxygen unloading from hemoglobin?

Increased temperature enhances O$_2$ unloading from hemoglobin.

Increased temperature causes hemoglobin to bind O$_2$ more tightly.

Increased temperature has no effect on O$_2$ unloading from hemoglobin.

Increased temperature decreases O$_2$ unloading from hemoglobin.

Previous problemNext problem

Verified step by step guidance

Understand the relationship between temperature and hemoglobin's oxygen-binding affinity. Hemoglobin's ability to bind oxygen is influenced by environmental factors, including temperature. Increased temperature typically reduces hemoglobin's affinity for oxygen, facilitating oxygen unloading to tissues.

Recall the Bohr effect, which describes how changes in pH and CO$_2$ levels affect hemoglobin's oxygen-binding affinity. While the Bohr effect primarily focuses on pH and CO$_2$, temperature also plays a role in modulating hemoglobin's behavior.

Consider the physiological context: during exercise or fever, body temperature increases, and tissues require more oxygen. Enhanced oxygen unloading from hemoglobin at higher temperatures supports this increased demand.

Analyze the options provided: The correct statement should align with the concept that increased temperature enhances oxygen unloading from hemoglobin, as hemoglobin's affinity for oxygen decreases under these conditions.

Conclude that the correct answer is: 'Increased temperature enhances O$_2$ unloading from hemoglobin,' based on the biochemical principles governing hemoglobin's oxygen-binding affinity and the physiological need for oxygen delivery to tissues.