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Multiple Choice
Which of the following amino acids is classified as a basic amino acid?
A
Aspartic acid
B
Lysine
C
Serine
D
Valine
Verified step by step guidance
1
Step 1: Understand the classification of amino acids based on their side chain properties. Amino acids can be categorized as acidic, basic, polar, or nonpolar depending on the chemical nature of their R-group (side chain). Basic amino acids have positively charged side chains at physiological pH.
Step 2: Recall the structures of the amino acids listed in the problem. Aspartic acid has a negatively charged carboxyl group in its side chain, making it acidic. Serine has a hydroxyl group, making it polar but not basic. Valine has a nonpolar, hydrophobic side chain. Lysine has an amino group in its side chain, which is positively charged at physiological pH, classifying it as a basic amino acid.
Step 3: Compare the side chains of the amino acids provided. Identify which amino acid has a positively charged group at physiological pH, as this is the defining characteristic of basic amino acids.
Step 4: Confirm that Lysine is the correct answer because its side chain contains an amino group (-NH3+) that is protonated and positively charged at physiological pH, fitting the definition of a basic amino acid.
Step 5: Conclude that Aspartic acid, Serine, and Valine do not meet the criteria for basic amino acids based on their side chain properties, while Lysine does.