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Multiple Choice
Which of the following is NOT a product of glycolysis (per molecule of glucose under aerobic conditions)?
A
ATP (net)
B
Acetyl-CoA
C
NADH
D
Pyruvate
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Verified step by step guidance
1
Step 1: Understand the glycolysis pathway, which breaks down one molecule of glucose (6 carbons) into two molecules of pyruvate (3 carbons each).
Step 2: Identify the main products formed directly during glycolysis: ATP (net gain of 2 molecules), NADH (2 molecules), and pyruvate (2 molecules).
Step 3: Recognize that Acetyl-CoA is not produced during glycolysis itself; instead, it is formed later in the mitochondria when pyruvate is converted by the pyruvate dehydrogenase complex.
Step 4: Compare each option to the known glycolysis products: ATP (net), NADH, and pyruvate are all direct products, while Acetyl-CoA is not.
Step 5: Conclude that Acetyl-CoA is NOT a product of glycolysis per se, but a product of the subsequent step linking glycolysis to the citric acid cycle.