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Multiple Choice
Which of the following is NOT a net product of glycolysis (per 1 molecule of glucose under aerobic conditions)?
A
Acetyl-CoA
B
NADH
C
ATP
D
Pyruvate
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Verified step by step guidance
1
Step 1: Understand the overall process of glycolysis. Glycolysis is the metabolic pathway that converts one molecule of glucose (a 6-carbon sugar) into two molecules of pyruvate (3-carbon compounds), producing energy in the form of ATP and reducing equivalents in the form of NADH.
Step 2: Identify the net products of glycolysis per one molecule of glucose. Glycolysis produces 2 molecules of ATP (net gain), 2 molecules of NADH, and 2 molecules of pyruvate. These are the direct outputs of the glycolytic pathway.
Step 3: Recognize that Acetyl-CoA is not produced during glycolysis itself. Instead, pyruvate is converted into Acetyl-CoA in a separate step called the pyruvate dehydrogenase complex reaction, which occurs after glycolysis and before the citric acid cycle.
Step 4: Summarize the net products of glycolysis as: 2 ATP, 2 NADH, and 2 pyruvate molecules per glucose. Since Acetyl-CoA is formed after glycolysis, it is not a net product of glycolysis.
Step 5: Conclude that among the options given, Acetyl-CoA is NOT a net product of glycolysis, while NADH, ATP, and pyruvate are.