Multiple Choice
In cellular respiration, what is the main function of the Krebs (citric acid) cycle?
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Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism
Citric Acid Cycle 1
Multiple Choice
In eukaryotic cells, where do the reactions of the citric acid (TCA) cycle primarily occur?
A
On the outer mitochondrial membrane
B
In the nucleus
C
In the mitochondrial matrix
D
In the cytosol
Verified step by step guidance1
Understand the location of the citric acid (TCA) cycle within eukaryotic cells by recalling the cellular compartments involved in metabolism.
Recall that the mitochondrion has several distinct parts: the outer mitochondrial membrane, the intermembrane space, the inner mitochondrial membrane, and the mitochondrial matrix.
Recognize that the TCA cycle enzymes are located in the mitochondrial matrix, which is the innermost compartment of the mitochondrion.
Eliminate other options by noting that the outer mitochondrial membrane is primarily a barrier and site for transport, the nucleus is the site of genetic material storage and transcription, and the cytosol is where glycolysis occurs, not the TCA cycle.
Conclude that the reactions of the citric acid cycle primarily occur in the mitochondrial matrix, where the enzymes and substrates are localized for efficient energy metabolism.
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