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Multiple Choice
In glycolysis, what best describes the energy investment phase?
A
The phase in which NADH and ATP are produced from glyceraldehyde-3-phosphate to pyruvate (steps 6–10).
B
The first phase in which ATP is consumed to phosphorylate glucose and form fructose-1,6-bisphosphate (steps 1–5).
C
The pathway in which glucose is oxidized to while producing ATP directly from glucose.
D
The conversion of pyruvate to lactate to regenerate under anaerobic conditions.
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Verified step by step guidance
1
Understand that glycolysis is divided into two main phases: the energy investment phase and the energy payoff phase.
Recognize that the energy investment phase involves the consumption of ATP to prepare glucose for subsequent breakdown.
Identify that during this phase (steps 1–5), glucose is phosphorylated first to glucose-6-phosphate and then converted to fructose-1,6-bisphosphate, using ATP molecules.
Note that this phosphorylation is essential because it traps glucose inside the cell and destabilizes it, making it more reactive for later steps.
Contrast this with the energy payoff phase (steps 6–10), where ATP and NADH are produced as glyceraldehyde-3-phosphate is converted to pyruvate.