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Multiple Choice
Which of the following is a direct product of one turn of the citric acid (Krebs) cycle per acetyl-CoA oxidized?
A
B
C
D
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1
Understand that one turn of the citric acid cycle (Krebs cycle) begins with the condensation of acetyl-CoA with oxaloacetate to form citrate, and through a series of reactions, regenerates oxaloacetate while producing energy-rich molecules.
Recall the main products generated directly per acetyl-CoA oxidized in one turn of the cycle: 3 molecules of NADH, 1 molecule of FADH2, 1 molecule of GTP (or ATP), and 2 molecules of CO2 as waste.
Identify that NADH and FADH2 are electron carriers that will later donate electrons to the electron transport chain, while GTP (or ATP) is a direct energy currency molecule produced in the cycle.
Note that glucose (C6H12O6) is not a product of the citric acid cycle; it is actually the starting molecule for glycolysis, which precedes the citric acid cycle.
Conclude that the direct products per acetyl-CoA oxidized include NADH, FADH2, and GTP (or ATP), with NADH being a key product as indicated in the problem.