Multiple Choice
Which of the following is a direct product of one turn of the citric acid (Krebs) cycle per acetyl-CoA oxidized?
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Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism
Citric Acid Cycle 1
Multiple Choice
In aerobic metabolism, what is the primary function of the citric acid (Krebs) cycle?
A
Break down glucose into two molecules of pyruvate while generating ATP and
B
Directly use as the terminal electron acceptor to form water and drive ATP synthesis
C
Oxidize acetyl-CoA to while producing , , and (or ATP)
D
Synthesize acetyl-CoA from fatty acids by repeated removal of two-carbon units while producing and
Verified step by step guidance1
Understand that the citric acid cycle (Krebs cycle) is a central metabolic pathway in aerobic respiration that processes acetyl-CoA derived from carbohydrates, fats, and proteins.
Recognize that the primary function of the citric acid cycle is to oxidize acetyl-CoA to carbon dioxide (CO\_2), which involves a series of enzyme-catalyzed reactions.
Note that during this oxidation process, the cycle generates high-energy electron carriers: NADH and FADH\_2, which are essential for the electron transport chain to produce ATP.
Also, the cycle produces a molecule of GTP (or ATP depending on the cell type) directly through substrate-level phosphorylation.
Distinguish this function from other processes such as glycolysis (which breaks down glucose to pyruvate), the electron transport chain (which uses O\_2 as the terminal electron acceptor), and beta-oxidation (which breaks down fatty acids to acetyl-CoA).
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