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Multiple Choice
In the citric acid (Krebs) cycle, which set of products is generated per acetyl-CoA oxidized (not counting the NADH and FADH2 made later in the electron transport chain)?
A
, , and with no released
B
and (oxidized coenzymes) plus
C
, , (or ATP), and
D
, , and
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Verified step by step guidance
1
Recall that one turn of the citric acid (Krebs) cycle oxidizes one acetyl-CoA molecule, producing reduced coenzymes and high-energy phosphate compounds along with carbon dioxide.
Identify the key products formed directly in the cycle per acetyl-CoA: NADH, FADH2, GTP (or ATP), and CO2. These are generated before the electron transport chain processes NADH and FADH2 further.
Remember the stoichiometry of the cycle: for each acetyl-CoA oxidized, 3 molecules of NADH are produced by the reduction of NAD+, 1 molecule of FADH2 is produced by the reduction of FAD, 1 molecule of GTP (or ATP) is generated by substrate-level phosphorylation, and 2 molecules of CO2 are released as waste carbon atoms.
Write the balanced summary of products per acetyl-CoA as: 3 NADH + 1 FADH2 + 1 GTP (or ATP) + 2 CO2.
Understand that this set of products reflects the direct output of the citric acid cycle itself, not counting the further ATP generated later in the electron transport chain from NADH and FADH2 oxidation.