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Multiple Choice
Which of the following biochemical reactions is catalyzed by a ribozyme?
A
Oxidation of succinate to fumarate
B
Hydrolysis of ATP to ADP and Pi
C
Conversion of glucose to glucose-6-phosphate
D
Peptide bond formation during protein synthesis
Verified step by step guidance
1
Understand the concept of a ribozyme: A ribozyme is an RNA molecule that acts as a catalyst in biochemical reactions, similar to protein enzymes. Ribozymes are unique because they are composed of RNA rather than protein.
Identify the reaction catalyzed by a ribozyme: Ribozymes are known to catalyze specific reactions, such as peptide bond formation during protein synthesis, which occurs in the ribosome.
Analyze the options provided: The oxidation of succinate to fumarate, hydrolysis of ATP to ADP and Pi, and conversion of glucose to glucose-6-phosphate are all catalyzed by protein enzymes, not ribozymes.
Focus on peptide bond formation: During protein synthesis, the ribosome facilitates the formation of peptide bonds between amino acids. The ribosome's catalytic activity is carried out by its RNA component, specifically the rRNA in the large subunit, making this reaction ribozyme-catalyzed.
Conclude that peptide bond formation during protein synthesis is the correct answer because it is the only reaction listed that is catalyzed by a ribozyme.