Multiple Choice
Which of the following is the primary net product of glycolysis per molecule of glucose under aerobic conditions?
8
views
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Glycolysis 1
Multiple Choice
In glycolysis, what is the role of produced by glyceraldehyde-3-phosphate dehydrogenase?
A
It is consumed by hexokinase to convert glucose to glucose-6-phosphate.
B
It carries high-energy electrons to the electron transport chain (after being shuttled into mitochondria) for ATP production via oxidative phosphorylation.
C
It is oxidized back to by converting pyruvate to acetyl-CoA in the cytosol.
D
It directly phosphorylates to make ATP in the phosphoglycerate kinase step.
Verified step by step guidance1
Understand that NADH is produced during glycolysis by the enzyme glyceraldehyde-3-phosphate dehydrogenase, which catalyzes the oxidation of glyceraldehyde-3-phosphate.
Recognize that NADH functions as an electron carrier, meaning it temporarily holds high-energy electrons removed from substrates during metabolic reactions.
Recall that NADH cannot directly phosphorylate ADP to ATP in glycolysis; instead, it must transfer its electrons to the electron transport chain (ETC) located in the mitochondria.
Note that the electrons carried by NADH are shuttled into the mitochondria where they enter the ETC, leading to the generation of a proton gradient used to produce ATP via oxidative phosphorylation.
Conclude that the primary role of NADH produced in glycolysis is to carry high-energy electrons to the ETC for ATP production, rather than being consumed by hexokinase, oxidized in the cytosol, or directly phosphorylating ADP.
Related Videos
Related Practice
