Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

Biochemistry

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

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Multiple Choice

Which of the following statements best explains the name of the 'induced fit model' in enzyme-substrate interactions?

The enzyme and substrate have perfectly complementary shapes before binding.

The substrate is forced to fit into the rigid active site of the enzyme.

The enzyme changes its shape to better accommodate the substrate upon binding.

The enzyme permanently alters its structure after binding the substrate.

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Verified step by step guidance

Understand the concept of the 'induced fit model' in enzyme-substrate interactions. This model describes how enzymes are flexible and can change their shape to better accommodate the substrate upon binding.

Compare the given statements to the induced fit model. The first statement, 'The enzyme and substrate have perfectly complementary shapes before binding,' aligns with the older 'lock and key model,' not the induced fit model.

Evaluate the second statement, 'The substrate is forced to fit into the rigid active site of the enzyme.' This is incorrect because the induced fit model emphasizes enzyme flexibility, not rigidity.

Analyze the third statement, 'The enzyme changes its shape to better accommodate the substrate upon binding.' This aligns with the induced fit model, as it highlights the enzyme's ability to adapt its shape for optimal interaction with the substrate.

Review the fourth statement, 'The enzyme permanently alters its structure after binding the substrate.' This is incorrect because the induced fit model involves temporary changes in enzyme shape, which revert after the reaction is complete.