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Multiple Choice
Proteins are much more difficult to study than DNA because many proteins are modified after which of the following processes?
A
Transcription
B
Splicing
C
Replication
D
Translation
Verified step by step guidance
1
Understand the central dogma of molecular biology, which describes the flow of genetic information: DNA is transcribed into RNA, and RNA is translated into proteins. Proteins are the final product of this process.
Recognize that proteins undergo post-translational modifications (PTMs) after translation. These modifications can include phosphorylation, glycosylation, acetylation, and more, which alter the protein's structure and function.
Compare the processes listed in the question: Transcription involves synthesizing RNA from DNA, Splicing modifies RNA by removing introns, and Replication duplicates DNA. None of these processes involve proteins directly.
Focus on translation, which is the process where ribosomes synthesize proteins using mRNA as a template. After translation, proteins are subject to modifications that make them functional and biologically active.
Conclude that proteins are difficult to study because their structure and function are influenced by these post-translational modifications, which add complexity beyond the genetic code.