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Multiple Choice
Which of the following statements about amino acids is correct?
A
Amino acids with nonpolar side chains are always charged at physiological pH.
B
Glycine is the only amino acid with a chiral alpha carbon.
C
All amino acids contain a sulfur atom in their side chain.
D
All amino acids found in proteins are L-isomers.
Verified step by step guidance
1
Step 1: Understand the structure of amino acids. Amino acids are the building blocks of proteins and consist of a central alpha carbon bonded to four groups: an amino group (-NH2), a carboxyl group (-COOH), a hydrogen atom, and a unique side chain (R group).
Step 2: Analyze the first statement: 'Amino acids with nonpolar side chains are always charged at physiological pH.' Nonpolar side chains are hydrophobic and do not ionize, so they are not charged at physiological pH (~7.4). This statement is incorrect.
Step 3: Analyze the second statement: 'Glycine is the only amino acid with a chiral alpha carbon.' Glycine is unique because its side chain is a hydrogen atom, making it achiral (not chiral). Most other amino acids have a chiral alpha carbon. This statement is incorrect.
Step 4: Analyze the third statement: 'All amino acids contain a sulfur atom in their side chain.' Only two amino acids, cysteine and methionine, contain sulfur in their side chains. This statement is incorrect.
Step 5: Analyze the fourth statement: 'All amino acids found in proteins are L-isomers.' Amino acids in proteins are exclusively L-isomers, as opposed to D-isomers, which are not used in protein synthesis. This statement is correct.