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Multiple Choice
Which of the following statements is true regarding a basic amino acid?
A
It contains a side chain with a positive charge at physiological pH.
B
It is always hydrophobic in nature.
C
It contains a side chain with a carboxyl group.
D
It cannot participate in hydrogen bonding.
Verified step by step guidance
1
Understand the definition of a basic amino acid: Basic amino acids have side chains that are positively charged at physiological pH (around 7.4). Examples include lysine, arginine, and histidine.
Analyze the first statement: 'It contains a side chain with a positive charge at physiological pH.' This aligns with the definition of basic amino acids, as their side chains typically contain functional groups like amines that are protonated and positively charged at physiological pH.
Evaluate the second statement: 'It is always hydrophobic in nature.' Hydrophobicity refers to the tendency to repel water. Basic amino acids are generally hydrophilic due to their charged side chains, which interact well with water. Thus, this statement is incorrect.
Examine the third statement: 'It contains a side chain with a carboxyl group.' Carboxyl groups (-COOH) are characteristic of acidic amino acids, not basic amino acids. Therefore, this statement is incorrect.
Assess the fourth statement: 'It cannot participate in hydrogen bonding.' Basic amino acids can participate in hydrogen bonding due to the presence of polar and charged groups in their side chains. This statement is also incorrect.