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Multiple Choice
Which molecule acts as an enzyme during the formation of peptide bonds between amino acids?
A
Transfer RNA (tRNA)
B
Messenger RNA (mRNA)
C
DNA polymerase
D
Ribosomal RNA (rRNA)
Verified step by step guidance
1
Understand the context: Peptide bond formation occurs during protein synthesis, specifically in the ribosome, where amino acids are joined together to form a polypeptide chain.
Recall the role of ribosomal RNA (rRNA): rRNA is a structural and functional component of the ribosome. It plays a catalytic role in the formation of peptide bonds, acting as a ribozyme (an RNA molecule with enzymatic activity).
Eliminate incorrect options: Transfer RNA (tRNA) is involved in bringing amino acids to the ribosome, but it does not catalyze peptide bond formation. Messenger RNA (mRNA) provides the template for translation but does not have enzymatic activity. DNA polymerase is involved in DNA replication, not protein synthesis.
Focus on the correct answer: Ribosomal RNA (rRNA) is the molecule that catalyzes the formation of peptide bonds between amino acids during translation. Specifically, the peptidyl transferase activity is associated with the large subunit of the ribosome.
Conclude: The correct answer is ribosomal RNA (rRNA), as it acts as an enzyme during the formation of peptide bonds between amino acids in the ribosome.