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Multiple Choice
Which set of molecules represents the net products produced per one acetyl-CoA oxidized in a single turn of the citric acid (Krebs) cycle (not including oxidative phosphorylation)?
A
, , , and
B
, , , and
C
, , (or ), and
D
, , , and
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Verified step by step guidance
1
Recall that one turn of the citric acid cycle begins with the oxidation of one acetyl-CoA molecule, which combines with oxaloacetate to form citrate.
Identify the key products generated during the cycle before oxidative phosphorylation: NADH, FADH2, GTP (or ATP), and CO2 molecules.
Remember that for each acetyl-CoA oxidized, the cycle produces 3 molecules of NADH by three separate dehydrogenase reactions.
Note that 1 molecule of FADH2 is produced during the conversion of succinate to fumarate.
Recognize that 1 molecule of GTP (which can be converted to ATP) is generated via substrate-level phosphorylation, and 2 molecules of CO2 are released as the acetyl group is fully oxidized.