So this practice problem wants us to select the one potential answer option down below that best corresponds with prenelated proteins. Now, of course, we know from our previous lesson videos that prenylated proteins are one of the 4 different types of lipid linked membrane proteins. And, of course, the prene in the prenylated proteins is referring to the fact that these proteins are covalently attached to an isoprenoid. And of course, because these are linked to isoprenoids, they're not going to be linked to fatty acid chains such as what option b and option c both indicate. Because recall that fatty acids are a completely different type of lipid than isoprenoids. And so for that reason, we can go ahead and eliminate both option b and option c. Now we know that lipid linked membrane proteins are a type of peripheral membrane protein, and that's because the protein part remains on the periphery, whereas the lipid linked part is the only part that is integrated into the membrane. But again, the protein itself is not integrated into the membrane, which means that predelinated proteins are not integral membrane proteins. And so for that reason, we can eliminate option a. Now option d says that preneleted proteins are post translationally modified proteins. And of course, recall from our previous lesson videos that this these are just modifications that occur after translation. So post is the prefix for after, and translationally is referring to translation. So these are modifications that occur after translation. And of course, when the protein is first translated, it's just gonna contain amino acids. And so any covalent modification that occurs to the protein after that, such as, covalently linking a lipid, that will be referred to as post translational modifications. And so option d here is the correct answer to this problem, so we can eliminate option e. And so that concludes this practice and I'll see you guys in our next video.

Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

10. Lipids

Lipid-Linked Membrane Proteins

Biochemistry

10. Lipids

Lipid-Linked Membrane Proteins

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Multiple Choice

Prenylated proteins:

Are integral membrane proteins.

Contain amide linkages to straight-chain fatty acids.

Contain ester linkages to straight-chain fatty acids.

Are post-translationally modified proteins.

None of the above.

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Verified step by step guidance

Understand the concept of prenylation: Prenylation is a type of post-translational modification where hydrophobic molecules, such as farnesyl or geranylgeranyl groups, are added to proteins. This modification helps anchor proteins to cell membranes.

Evaluate option a: Integral membrane proteins are proteins that are permanently attached to the membrane. While prenylation helps proteins associate with membranes, it does not make them integral membrane proteins.

Evaluate option b: Amide linkages involve a bond between a carboxyl group and an amine group. Prenylation does not involve amide linkages to straight-chain fatty acids.

Evaluate option c: Ester linkages involve a bond between a carboxyl group and an alcohol group. Prenylation does not involve ester linkages to straight-chain fatty acids.

Evaluate option d: Recognize that prenylated proteins are indeed post-translationally modified, as prenylation occurs after the protein is synthesized. This modification is crucial for the protein's function and localization.