Question 1

Which of the following best describes the net reaction of glycolysis in terms of reactants and products?

Accepted Answer

$$\mathrm{Glucose + 2\ ADP + 2\ NAD^+ + 2\ Pi \rightarrow 2\ pyruvate + 2\ ATP + 2\ NADH + 2\ H^+ + 2\ H_2O}$$

Question 2

Which of the following sugars can enter glycolysis after being converted to fructose-6-phosphate?

Accepted Answer

Mannose

Question 3

In anaerobic conditions in mammalian muscle cells, what is the primary fate of pyruvate?

Accepted Answer

Conversion to lactate

Question 4

Which enzyme is responsible for converting galactose to glucose-6-phosphate so it can enter glycolysis?

Accepted Answer

Galactokinase

Question 5

What is the net ATP yield per molecule of glucose during glycolysis?

Accepted Answer

$$2$$

Question 6

Which of the following is a correct description of the fate of pyruvate under aerobic conditions?

Accepted Answer

Pyruvate is converted to acetyl CoA, which enters the citric acid cycle.

Question 7

A patient with galactosemia is unable to properly metabolize galactose. Which metabolic pathway is directly affected?

Accepted Answer

Entry of galactose into glycolysis

Question 8

Which of the following best explains why glycolysis is considered an anaerobic pathway?

Accepted Answer

It does not require molecular oxygen ($$O_2) to $$proceed.

Question 9

Which of the following is a possible fate of pyruvate in yeast cells under anaerobic conditions?

Accepted Answer

Conversion to ethanol

Question 10

If a mutation prevents the formation of NADH during glycolysis, which of the following processes would be directly impaired?

Accepted Answer

Reduction of pyruvate to lactate

Question 11

Which of the following statements about the entry of dietary sugars into glycolysis is correct?

Accepted Answer

Fructose, galactose, and mannose all yield a net of 2 ATP per molecule when entering glycolysis.

Question 12

Which of the following best describes the role of NAD+ in glycolysis?

Accepted Answer

It acts as an electron acceptor, becoming reduced to NADH.

Question 13

A person with lactose intolerance cannot digest lactose. Which sugar is not efficiently entering glycolysis in this individual?

Accepted Answer

Galactose

Question 14

Which of the following is NOT a product of glycolysis?

Accepted Answer

Acetyl CoA

Question 15

Which of the following equations correctly represents the conversion of pyruvate to lactate?

Accepted Answer

$$\mathrm{Pyruvate + NADH + H^+ \rightarrow Lactate + NAD^+}$$

Question 16

Which of the following best explains why glycolysis is essential for red blood cells?

Accepted Answer

Red blood cells lack mitochondria and rely solely on glycolysis for ATP production.

Glycolysis: Pathway, Energy Yield, and Metabolic Fates

Study Guide - Practice Questions