Multiple Choice
Which process would be most directly affected if the 5' cap is not added to an mRNA?
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15. Gene Expression
Eukaryotic RNA Processing and Splicing
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Which of the following mRNAs could be processed from a pre-mRNA that undergoes alternative splicing?
A
An mRNA with exons 1, 2, and 3
B
An mRNA with only introns
C
An mRNA with exons 2 and 3, but not exon 1
D
An mRNA with exons 1 and 3, but not exon 2
Verified step by step guidance1
Understand the concept of alternative splicing: Alternative splicing is a process by which different combinations of exons are joined together to produce multiple mRNA variants from a single pre-mRNA transcript. This allows a single gene to code for multiple proteins.
Identify the components of pre-mRNA: Pre-mRNA consists of exons and introns. Exons are sequences that code for proteins, while introns are non-coding sequences that are removed during RNA processing.
Recognize the possible outcomes of alternative splicing: Since alternative splicing can result in different combinations of exons, the mRNA variants can include different sets of exons while excluding others.
Evaluate the given options: Consider each mRNA variant option and determine if it is a plausible result of alternative splicing. Exclude any option that consists solely of introns, as introns are removed during processing.
Select the correct mRNA variants: Based on the understanding of alternative splicing, identify the mRNA variants that include different combinations of exons, such as those with exons 1, 2, and 3; exons 2 and 3; and exons 1 and 3.
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