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Multiple Choice
Which of the following is NOT a function of the 3' poly-A tail in eukaryotic RNA processing?
A
Enhancing mRNA stability
B
Facilitating nuclear export of mRNA
C
Assisting in the initiation of translation
D
Promoting RNA splicing
Verified step by step guidance
1
Understand the role of the 3' poly-A tail in eukaryotic RNA processing. The poly-A tail is a stretch of adenine nucleotides added to the 3' end of a pre-mRNA molecule.
Recognize that one of the primary functions of the poly-A tail is to enhance mRNA stability by protecting it from enzymatic degradation in the cytoplasm.
Identify that the poly-A tail also facilitates the export of mRNA from the nucleus to the cytoplasm, where translation occurs.
Acknowledge that the poly-A tail plays a role in the initiation of translation by interacting with proteins that help recruit the ribosome to the mRNA.
Note that promoting RNA splicing is not a function of the 3' poly-A tail. RNA splicing is primarily facilitated by the spliceosome, which removes introns from pre-mRNA.