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Multiple Choice
Hemophilia is a recessive sex-linked genetic disorder. Which statement is true about this condition?
A
Hemophilia is more common in males because they have only one X chromosome.
B
Hemophilia is passed from father to son through the Y chromosome.
C
Hemophilia carriers are typically male because they have two X chromosomes.
D
Hemophilia affects males and females equally because it is autosomal.
Verified step by step guidance
1
Understand that hemophilia is a recessive sex-linked disorder, which means it is associated with the sex chromosomes, specifically the X chromosome.
Recognize that males have one X and one Y chromosome (XY), while females have two X chromosomes (XX). This difference in chromosome composition is crucial for understanding the inheritance pattern of sex-linked disorders.
Since hemophilia is recessive and linked to the X chromosome, a male with one affected X chromosome will express the disorder because he does not have a second X chromosome to potentially mask the recessive allele.
Females would need two copies of the affected X chromosome to express hemophilia, making it less common in females. However, females can be carriers if they have one affected X chromosome and one normal X chromosome.
Evaluate the statements: Hemophilia is more common in males because they have only one X chromosome, making them more likely to express the disorder if they inherit the affected X chromosome.