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Multiple Choice
At what stage of the cell cycle is the cyclin component of MPF (Maturation Promoting Factor) destroyed?
A
G2 phase
B
G1 phase
C
M phase
D
S phase
Verified step by step guidance
1
Understand the role of MPF (Maturation Promoting Factor) in the cell cycle. MPF is a complex of cyclin and cyclin-dependent kinase (CDK) that is crucial for the progression of the cell cycle from the G2 phase to the M phase.
Recognize that cyclins are proteins whose levels fluctuate throughout the cell cycle. They are synthesized and degraded at specific stages to regulate the cycle's progression.
Identify that the M phase, or mitosis, is the stage where the cell divides its chromosomes into two daughter cells. MPF activity is highest during the transition from G2 to M phase, facilitating the onset of mitosis.
Note that the cyclin component of MPF is destroyed during the M phase. This degradation is necessary to exit mitosis and enter the G1 phase, ensuring that the cell cycle does not proceed without proper regulation.
Understand that the destruction of cyclin during the M phase is a key regulatory mechanism that prevents premature or uncontrolled cell division, maintaining the integrity of the cell cycle.