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Multiple Choice
A cell has damaged DNA. Which checkpoint is responsible for checking this?
A
M checkpoint
B
S checkpoint
C
G1 checkpoint
D
G2 checkpoint
Verified step by step guidance
1
Understand the cell cycle: The cell cycle consists of several phases, including G1, S, G2, and M phases. Each phase has specific checkpoints that ensure the cell is ready to proceed to the next stage.
Identify the role of each checkpoint: The G1 checkpoint checks for DNA damage before the cell enters the S phase. The S checkpoint ensures DNA is replicated correctly. The G2 checkpoint checks for DNA damage after DNA replication and before mitosis. The M checkpoint ensures all chromosomes are properly aligned before cell division.
Focus on DNA damage: Since the problem involves damaged DNA, we need to identify which checkpoint is responsible for detecting DNA damage.
Determine the correct checkpoint: The G1 checkpoint is primarily responsible for checking DNA damage before the cell commits to DNA replication in the S phase.
Conclude the solution: Based on the roles of each checkpoint, the G1 checkpoint is the one responsible for checking DNA damage, ensuring the cell does not proceed with damaged DNA.