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Multiple Choice
During which phase of mitosis does the nuclear membrane dissolve and the spindle apparatus begin to form?
A
Metaphase
B
Anaphase
C
Telophase
D
Prophase
Verified step by step guidance
1
Understand the question: The problem is asking about the phase of mitosis during which the nuclear membrane dissolves and the spindle apparatus begins to form. This requires knowledge of the stages of mitosis and their key events.
Recall the stages of mitosis: Mitosis consists of Prophase, Metaphase, Anaphase, and Telophase. Each phase has distinct cellular events that contribute to the division of the nucleus.
Focus on Prophase: During Prophase, the chromatin condenses into visible chromosomes, the nuclear membrane begins to break down, and the spindle apparatus (composed of microtubules) starts to form from the centrosomes.
Eliminate incorrect options: Metaphase involves the alignment of chromosomes at the metaphase plate, Anaphase involves the separation of sister chromatids, and Telophase involves the reformation of the nuclear membrane. These events occur after Prophase.
Conclude that Prophase is the correct answer: Based on the description of events, Prophase is the phase where the nuclear membrane dissolves and the spindle apparatus begins to form.