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Multiple Choice
Which enzyme covalently links the sugar-phosphate backbone of DNA during replication?
A
Helicase
B
Primase
C
DNA polymerase
D
DNA ligase
Verified step by step guidance
1
Understand the role of each enzyme listed in the options: Helicase, Primase, DNA polymerase, and DNA ligase.
Helicase is responsible for unwinding the DNA double helix, creating two single strands that serve as templates for replication.
Primase synthesizes a short RNA primer that provides a starting point for DNA polymerase to begin DNA synthesis.
DNA polymerase is the enzyme that adds nucleotides to the growing DNA strand, using the template strand as a guide.
DNA ligase is the enzyme that covalently links the sugar-phosphate backbone of DNA, sealing nicks and joining Okazaki fragments on the lagging strand during DNA replication.