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Multiple Choice
Which of the following are necessary for a cell to pass the G1 checkpoint?
A
Sufficient cell size and nutrients
B
Attachment of all chromosomes to the spindle
C
Completion of DNA replication
D
Presence of growth factors
Verified step by step guidance
1
Understand the role of the G1 checkpoint in the cell cycle. The G1 checkpoint is a critical control point where the cell assesses whether it is ready to proceed with the cell cycle and enter the S phase, where DNA replication occurs.
Identify the conditions necessary for a cell to pass the G1 checkpoint. These include sufficient cell size, adequate nutrients, and the presence of growth factors. These factors ensure that the cell has the resources and signals needed to support DNA replication and cell division.
Recognize that the attachment of all chromosomes to the spindle and the completion of DNA replication are not requirements for the G1 checkpoint. These are relevant to later stages in the cell cycle, specifically the metaphase checkpoint and the G2 checkpoint, respectively.
Consider the role of growth factors in the G1 checkpoint. Growth factors are signaling molecules that stimulate cell growth and division. Their presence indicates that the external environment is favorable for cell proliferation.
Evaluate the cell's size and nutrient availability. A cell must be large enough and have sufficient nutrients to support the energy and biosynthetic demands of DNA replication and subsequent cell division.