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Multiple Choice
What type of inheritance pattern does Duchenne Muscular Dystrophy (DMD) follow?
A
Autosomal dominant
B
Autosomal recessive
C
X-linked recessive
D
Y-linked
Verified step by step guidance
1
Understand the concept of inheritance patterns: Inheritance patterns describe how genetic traits are passed from parents to offspring. Common patterns include autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive, and Y-linked.
Identify the chromosome involved: Duchenne Muscular Dystrophy (DMD) is linked to the X chromosome. This means it is not autosomal, as autosomal traits are linked to non-sex chromosomes.
Determine if the trait is dominant or recessive: X-linked recessive traits typically manifest in males more frequently than females because males have only one X chromosome. If a male inherits the recessive allele on the X chromosome, he will express the trait.
Consider the implications for females: Females have two X chromosomes, so they would need two copies of the recessive allele to express the trait. This makes X-linked recessive traits less common in females.
Conclude the inheritance pattern: Based on the involvement of the X chromosome and the recessive nature of the trait, Duchenne Muscular Dystrophy follows an X-linked recessive inheritance pattern.