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Multiple Choice
Which of the following are the two mechanisms of transcription termination in E. coli?
A
Rho-dependent and Rho-independent termination
B
Helicase-dependent and Rho-independent termination
C
Sigma factor and Rho-independent termination
D
Rho-dependent and Sigma factor termination
Verified step by step guidance
1
Understand that transcription termination in E. coli involves stopping the synthesis of RNA from DNA.
Learn that there are two main mechanisms for transcription termination in E. coli: Rho-dependent and Rho-independent termination.
Rho-dependent termination involves a protein called Rho, which is a helicase that binds to the RNA and moves towards the RNA polymerase, causing the termination of transcription.
Rho-independent termination relies on the formation of a hairpin structure in the RNA, followed by a sequence of uracil nucleotides, which destabilizes the interaction between the RNA and the DNA template, leading to termination.
Review the options given in the problem and identify the correct pair of mechanisms: Rho-dependent and Rho-independent termination.