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Multiple Choice
What mechanism contributes to the remarkably high fidelity of DNA replication?
A
Rapid replication speed
B
Random incorporation of nucleotides
C
High concentration of nucleotides
D
Proofreading by DNA polymerase
Verified step by step guidance
1
Understand the concept of DNA replication: DNA replication is the process by which a cell duplicates its DNA, ensuring that each daughter cell receives an exact copy of the genetic material.
Learn about the role of DNA polymerase: DNA polymerase is an enzyme responsible for synthesizing new DNA strands by adding nucleotides complementary to the template strand.
Explore the proofreading function of DNA polymerase: During DNA replication, DNA polymerase has a proofreading ability that allows it to detect and correct errors. If an incorrect nucleotide is incorporated, the enzyme can remove it and replace it with the correct one.
Recognize the importance of proofreading: This proofreading mechanism is crucial for maintaining the high fidelity of DNA replication, as it significantly reduces the error rate, ensuring accurate genetic information is passed on.
Consider other factors affecting replication fidelity: While proofreading is a key mechanism, other factors such as the speed of replication and nucleotide concentration can influence the process, but they do not directly contribute to the high fidelity like proofreading does.