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Multiple Choice
Which of the following statements about Okazaki fragments in E. coli is true?
A
Okazaki fragments are synthesized continuously on the leading strand.
B
Okazaki fragments are short DNA sequences synthesized on the lagging strand.
C
Okazaki fragments are synthesized in the 3' to 5' direction.
D
Okazaki fragments are joined together by DNA polymerase.
Verified step by step guidance
1
Understand that DNA replication involves the synthesis of new DNA strands from a template strand. This process occurs in the 5' to 3' direction.
Recognize that the leading strand is synthesized continuously in the direction of the replication fork movement, while the lagging strand is synthesized discontinuously.
Identify that Okazaki fragments are short sequences of DNA nucleotides synthesized discontinuously on the lagging strand during DNA replication.
Note that these fragments are synthesized in the 5' to 3' direction, opposite to the overall direction of the replication fork movement.
Understand that DNA ligase, not DNA polymerase, is the enzyme responsible for joining Okazaki fragments together to form a continuous DNA strand.