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Multiple Choice
Which enzyme is responsible for 'unzipping' the DNA double helix during DNA replication?
A
Ligase
B
Primase
C
Helicase
D
DNA polymerase
Verified step by step guidance
1
Understand the process of DNA replication: DNA replication is the process by which a cell duplicates its DNA before cell division. It involves several enzymes that work together to ensure the DNA is copied accurately.
Identify the role of each enzyme listed: Ligase is responsible for joining Okazaki fragments on the lagging strand. Primase synthesizes RNA primers needed to start the replication process. DNA polymerase adds nucleotides to the growing DNA strand and proofreads for errors.
Focus on the initial step of DNA replication: The DNA double helix must be unwound to allow replication to occur. This unwinding is crucial for the replication machinery to access the DNA strands.
Determine which enzyme unwinds the DNA: Helicase is the enzyme that 'unzips' or unwinds the DNA double helix by breaking the hydrogen bonds between the base pairs, allowing the two strands to separate.
Conclude the role of helicase: Helicase is essential for initiating DNA replication by providing single-stranded DNA templates for the other enzymes to work on, making it the correct answer for the enzyme responsible for 'unzipping' the DNA.