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Multiple Choice
Negative feedback inhibition occurs when:
A
an external signal amplifies the production of a specific hormone
B
the end product of a metabolic pathway inhibits an earlier step in the pathway
C
the end product of a pathway stimulates further production of itself
D
the initial substrate accelerates the activity of the first enzyme in the pathway
Verified step by step guidance
1
Understand the concept of negative feedback inhibition: It is a regulatory mechanism in which the end product of a metabolic pathway inhibits an earlier step in the pathway to prevent overproduction of the product.
Analyze the first option: 'An external signal amplifies the production of a specific hormone.' This describes a process of amplification, not inhibition, so it does not align with negative feedback inhibition.
Analyze the second option: 'The end product of a metabolic pathway inhibits an earlier step in the pathway.' This matches the definition of negative feedback inhibition, as the end product acts as a signal to stop or slow down the pathway.
Analyze the third option: 'The end product of a pathway stimulates further production of itself.' This describes positive feedback, not negative feedback, as it involves amplification rather than inhibition.
Analyze the fourth option: 'The initial substrate accelerates the activity of the first enzyme in the pathway.' This describes a process of activation, not inhibition, and is unrelated to negative feedback inhibition.