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Multiple Choice
Negative feedback inhibition is best described as:
A
A process in which the end product of a metabolic pathway inhibits an earlier step in the pathway
B
A mechanism where the initial substrate accelerates the activity of the pathway
C
A process in which the end product stimulates further production of itself
D
A type of feedback that only occurs in hormonal regulation
Verified step by step guidance
1
Step 1: Begin by understanding the concept of negative feedback inhibition. Negative feedback is a regulatory mechanism in which the end product of a process inhibits an earlier step in the pathway to prevent overproduction and maintain homeostasis.
Step 2: Analyze the options provided in the problem. The correct description of negative feedback inhibition should align with the idea that the end product acts as an inhibitor to control the pathway's activity.
Step 3: Eliminate options that do not match the definition of negative feedback inhibition. For example, options describing acceleration of activity or stimulation of further production are more characteristic of positive feedback, not negative feedback.
Step 4: Focus on the option that describes the end product inhibiting an earlier step in the pathway. This matches the definition of negative feedback inhibition and ensures the pathway is regulated effectively.
Step 5: Confirm that the chosen option aligns with biological principles of metabolic regulation, where negative feedback helps maintain balance and prevents excessive accumulation of the end product.