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Multiple Choice
Which of the following can disrupt the normal progression of the cell cycle?
A
G0 phase
B
Cancer
C
Mutation
D
Replication
Verified step by step guidance
1
Understand the cell cycle: The cell cycle is a series of stages (G1, S, G2, and M) that cells go through to grow and divide. Disruptions in this cycle can lead to abnormal cell behavior.
Define the G0 phase: The G0 phase is a resting state where cells exit the cycle and do not divide. While it halts progression, it does not disrupt the normal cycle itself.
Explain cancer's role: Cancer is characterized by uncontrolled cell division, often caused by disruptions in the cell cycle regulation. This is typically due to mutations in genes that control the cycle.
Clarify the role of mutations: Mutations in key regulatory genes (e.g., tumor suppressor genes or proto-oncogenes) can disrupt the normal progression of the cell cycle, leading to uncontrolled growth or failure to repair DNA damage.
Discuss replication: DNA replication occurs during the S phase of the cell cycle. Errors during replication can lead to mutations, which may disrupt the cycle if they affect regulatory mechanisms.