Multiple Choice
Which of the following is a known risk factor that increases an individual's chance of developing cancer?
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11. Cell Division
Cancer
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Which of the following is true about cancer cells?
A
They always undergo programmed cell death (apoptosis) when DNA is damaged.
B
They require external growth signals to continue dividing.
C
They can divide uncontrollably and evade normal cell cycle regulation.
D
They have a limited number of cell divisions before entering senescence.
Verified step by step guidance1
Step 1: Understand the characteristics of cancer cells. Cancer cells are known for their ability to evade normal cell cycle regulation, allowing them to divide uncontrollably. This is a key feature that distinguishes them from normal cells.
Step 2: Analyze the first statement: 'They always undergo programmed cell death (apoptosis) when DNA is damaged.' This is incorrect because cancer cells often avoid apoptosis, even when their DNA is damaged, which contributes to their uncontrolled growth.
Step 3: Evaluate the second statement: 'They require external growth signals to continue dividing.' This is incorrect because cancer cells can often produce their own growth signals or bypass the need for external signals, enabling them to divide autonomously.
Step 4: Assess the third statement: 'They can divide uncontrollably and evade normal cell cycle regulation.' This is correct because cancer cells bypass the regulatory mechanisms of the cell cycle, leading to unchecked proliferation.
Step 5: Examine the fourth statement: 'They have a limited number of cell divisions before entering senescence.' This is incorrect because cancer cells often activate mechanisms, such as the enzyme telomerase, to avoid senescence and continue dividing indefinitely.
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