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Multiple Choice
What rule is used to join the free nucleotides to the exposed bases of the DNA during replication?
A
Chargaff's rule
B
Hardy-Weinberg principle
C
Central dogma
D
Mendel's law
Verified step by step guidance
1
Understand the context of DNA replication: DNA replication is the process by which a cell duplicates its DNA, ensuring that each new cell receives a complete set of genetic instructions.
Identify the role of nucleotides: During DNA replication, free nucleotides in the cell are joined to the exposed bases of the DNA strand to form a new complementary strand.
Recognize Chargaff's rule: Chargaff's rule states that in DNA, the amount of adenine (A) is equal to thymine (T), and the amount of cytosine (C) is equal to guanine (G). This rule is crucial for the pairing of nucleotides during replication.
Apply Chargaff's rule to nucleotide pairing: During replication, adenine pairs with thymine and cytosine pairs with guanine. This complementary base pairing ensures the accuracy of DNA replication.
Distinguish Chargaff's rule from other concepts: The Hardy-Weinberg principle, Central dogma, and Mendel's law are important biological concepts but are not directly related to the process of nucleotide pairing during DNA replication.