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Multiple Choice
Which of the following statements is true regarding lipophilic hormones such as steroids?
A
They are hydrophilic and require transport proteins to move through the cytoplasm.
B
They are stored in vesicles and released by exocytosis upon stimulation.
C
They bind exclusively to cell surface receptors because they cannot cross the plasma membrane.
D
They can diffuse through the plasma membrane and bind to intracellular receptors.
Verified step by step guidance
1
Understand the nature of lipophilic hormones, such as steroids. Lipophilic hormones are nonpolar and hydrophobic, meaning they can easily pass through lipid bilayers like the plasma membrane.
Recognize that lipophilic hormones do not require transport proteins to move through the cytoplasm. Instead, they can diffuse freely within the cell due to their hydrophobic nature.
Note that lipophilic hormones are not stored in vesicles or released by exocytosis. They are synthesized on demand and diffuse out of the cell where they are produced.
Understand that lipophilic hormones do not bind exclusively to cell surface receptors. Their ability to cross the plasma membrane allows them to interact with intracellular receptors located in the cytoplasm or nucleus.
Conclude that lipophilic hormones, such as steroids, can diffuse through the plasma membrane and bind to intracellular receptors, which is the correct statement in this case.