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Multiple Choice
Which is the correct pathway of a protein through a cell as it is being synthesized and secreted?
A
Rough ER → Vesicle → Golgi apparatus → Plasma membrane
B
Vesicle → Rough ER → Golgi apparatus → Plasma membrane
C
Golgi apparatus → Rough ER → Vesicle → Plasma membrane
D
Rough ER → Golgi apparatus → Vesicle → Plasma membrane
Verified step by step guidance
1
Understand that proteins are synthesized by ribosomes, which are often attached to the Rough Endoplasmic Reticulum (Rough ER). This is the starting point for the protein synthesis and secretion pathway.
Once synthesized in the Rough ER, proteins are packaged into vesicles. These vesicles transport the proteins to the Golgi apparatus for further processing and modification.
In the Golgi apparatus, proteins undergo modifications such as glycosylation, which is the addition of sugar molecules, and are sorted for their final destinations.
After processing in the Golgi apparatus, proteins are again packaged into vesicles. These vesicles are directed towards the plasma membrane.
Finally, the vesicles fuse with the plasma membrane, and the proteins are secreted out of the cell. This completes the pathway: Rough ER → Golgi apparatus → Vesicle → Plasma membrane.