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Multiple Choice
What is the first step in the process of DNA replication?
A
Synthesis of RNA primers by primase
B
Joining of Okazaki fragments by DNA ligase
C
Binding of DNA polymerase to the template strand
D
Unwinding of the DNA double helix by helicase
Verified step by step guidance
1
Understand that DNA replication is the process by which a cell duplicates its DNA before cell division.
Recognize that the DNA double helix must be unwound to allow the replication machinery to access the template strands.
Identify the enzyme responsible for unwinding the DNA double helix, which is helicase.
Note that helicase breaks the hydrogen bonds between the complementary bases, separating the two strands of DNA.
Acknowledge that the unwinding of the DNA double helix by helicase is the first step in the process of DNA replication, setting the stage for subsequent steps like primer synthesis and polymerase binding.