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Multiple Choice
What is the primary function of topoisomerase during DNA replication?
A
To synthesize RNA primers
B
To unwind the DNA double helix
C
To join Okazaki fragments
D
To relieve the tension in the DNA strand
Verified step by step guidance
1
Understand the role of topoisomerase in DNA replication. Topoisomerase is an enzyme that helps manage the topology of DNA during replication.
Recognize that during DNA replication, the unwinding of the double helix by helicase creates tension and supercoiling ahead of the replication fork.
Learn that topoisomerase alleviates this tension by making temporary cuts in the DNA strands, allowing them to rotate and relieve the supercoiling.
Note that after relieving the tension, topoisomerase reseals the DNA strands, ensuring the integrity of the DNA molecule is maintained.
Conclude that the primary function of topoisomerase is to relieve the tension in the DNA strand during replication, facilitating smooth progression of the replication process.