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Multiple Choice
The binding of signal molecules to _____ results in the phosphorylation of tyrosines.
A
G protein-coupled receptors
B
receptor tyrosine kinases
C
ligand-gated ion channels
D
steroid hormone receptors
Verified step by step guidance
1
Understand the role of receptor tyrosine kinases (RTKs) in cell signaling. RTKs are membrane proteins that function as enzymes and are activated by the binding of signal molecules (ligands).
Learn that phosphorylation is a process where a phosphate group is added to a molecule, often a protein, to activate or deactivate its function. In RTKs, phosphorylation occurs on tyrosine residues.
Recognize that G protein-coupled receptors (GPCRs) and ligand-gated ion channels do not directly phosphorylate tyrosines. GPCRs activate intracellular signaling pathways via G proteins, while ligand-gated ion channels allow ions to pass through the membrane upon ligand binding.
Understand that steroid hormone receptors are intracellular receptors that bind steroid hormones and act as transcription factors, rather than phosphorylating tyrosines.
Conclude that receptor tyrosine kinases are the correct answer because they are specifically designed to phosphorylate tyrosines upon ligand binding, initiating downstream signaling pathways.