Table of contents
- 1. Introduction to Biology2h 42m
- 2. Chemistry3h 37m
- 3. Water1h 26m
- 4. Biomolecules2h 23m
- 5. Cell Components2h 26m
- 6. The Membrane2h 31m
- 7. Energy and Metabolism2h 0m
- 8. Respiration2h 40m
- 9. Photosynthesis2h 49m
- 10. Cell Signaling59m
- 11. Cell Division2h 47m
- 12. Meiosis2h 0m
- 13. Mendelian Genetics4h 44m
- Introduction to Mendel's Experiments7m
- Genotype vs. Phenotype17m
- Punnett Squares13m
- Mendel's Experiments26m
- Mendel's Laws18m
- Monohybrid Crosses19m
- Test Crosses14m
- Dihybrid Crosses20m
- Punnett Square Probability26m
- Incomplete Dominance vs. Codominance20m
- Epistasis7m
- Non-Mendelian Genetics12m
- Pedigrees6m
- Autosomal Inheritance21m
- Sex-Linked Inheritance43m
- X-Inactivation9m
- 14. DNA Synthesis2h 27m
- 15. Gene Expression3h 6m
- 16. Regulation of Expression3h 31m
- Introduction to Regulation of Gene Expression13m
- Prokaryotic Gene Regulation via Operons27m
- The Lac Operon21m
- Glucose's Impact on Lac Operon25m
- The Trp Operon20m
- Review of the Lac Operon & Trp Operon11m
- Introduction to Eukaryotic Gene Regulation9m
- Eukaryotic Chromatin Modifications16m
- Eukaryotic Transcriptional Control22m
- Eukaryotic Post-Transcriptional Regulation28m
- Eukaryotic Post-Translational Regulation13m
- 17. Viruses37m
- 18. Biotechnology2h 58m
- 19. Genomics17m
- 20. Development1h 5m
- 21. Evolution3h 1m
- 22. Evolution of Populations3h 53m
- 23. Speciation1h 37m
- 24. History of Life on Earth2h 6m
- 25. Phylogeny2h 31m
- 26. Prokaryotes4h 59m
- 27. Protists1h 12m
- 28. Plants1h 22m
- 29. Fungi36m
- 30. Overview of Animals34m
- 31. Invertebrates1h 2m
- 32. Vertebrates50m
- 33. Plant Anatomy1h 3m
- 34. Vascular Plant Transport1h 2m
- 35. Soil37m
- 36. Plant Reproduction47m
- 37. Plant Sensation and Response1h 9m
- 38. Animal Form and Function1h 19m
- 39. Digestive System1h 10m
- 40. Circulatory System1h 49m
- 41. Immune System1h 12m
- 42. Osmoregulation and Excretion50m
- 43. Endocrine System1h 4m
- 44. Animal Reproduction1h 2m
- 45. Nervous System1h 55m
- 46. Sensory Systems46m
- 47. Muscle Systems23m
- 48. Ecology3h 11m
- Introduction to Ecology20m
- Biogeography14m
- Earth's Climate Patterns50m
- Introduction to Terrestrial Biomes10m
- Terrestrial Biomes: Near Equator13m
- Terrestrial Biomes: Temperate Regions10m
- Terrestrial Biomes: Northern Regions15m
- Introduction to Aquatic Biomes27m
- Freshwater Aquatic Biomes14m
- Marine Aquatic Biomes13m
- 49. Animal Behavior28m
- 50. Population Ecology3h 41m
- Introduction to Population Ecology28m
- Population Sampling Methods23m
- Life History12m
- Population Demography17m
- Factors Limiting Population Growth14m
- Introduction to Population Growth Models22m
- Linear Population Growth6m
- Exponential Population Growth29m
- Logistic Population Growth32m
- r/K Selection10m
- The Human Population22m
- 51. Community Ecology2h 46m
- Introduction to Community Ecology2m
- Introduction to Community Interactions9m
- Community Interactions: Competition (-/-)38m
- Community Interactions: Exploitation (+/-)23m
- Community Interactions: Mutualism (+/+) & Commensalism (+/0)9m
- Community Structure35m
- Community Dynamics26m
- Geographic Impact on Communities21m
- 52. Ecosystems2h 36m
- 53. Conservation Biology24m
8. Respiration
Review of Aerobic Cellular Respiration
Problem 4
Textbook Question
Most of the CO₂ from cellular respiration is released during
a. Stage 1: Glycolysis
b. Stage 2: Pyruvate oxidation
c. Stage 2: The citric acid cycle
d. Stage 3: Oxidative phosphorylation

1
Understand the stages of cellular respiration: Cellular respiration consists of three main stages: glycolysis, pyruvate oxidation (including the citric acid cycle), and oxidative phosphorylation. Each stage has distinct roles in energy production and carbon dioxide release.
Recall the role of glycolysis: Glycolysis occurs in the cytoplasm and breaks down glucose into two molecules of pyruvate. This process does not release CO2 because glucose is only partially oxidized.
Examine pyruvate oxidation: Pyruvate oxidation occurs in the mitochondria, where pyruvate is converted into acetyl-CoA. During this process, one molecule of CO2 is released per pyruvate molecule, but this is not the primary stage where most CO2 is released.
Analyze the citric acid cycle: The citric acid cycle (also known as the Krebs cycle) occurs in the mitochondrial matrix. Acetyl-CoA is fully oxidized, releasing two molecules of CO2 per cycle. This is the stage where most of the CO2 from cellular respiration is released.
Consider oxidative phosphorylation: Oxidative phosphorylation involves the electron transport chain and chemiosmosis, which generate ATP. This stage does not release CO2, as it focuses on energy production rather than carbon oxidation.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Cellular Respiration
Cellular respiration is the metabolic process by which cells convert glucose and oxygen into energy, carbon dioxide, and water. It consists of several stages, including glycolysis, pyruvate oxidation, the citric acid cycle, and oxidative phosphorylation. Understanding this process is crucial for identifying where CO2 is produced and released.
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Citric Acid Cycle
The citric acid cycle, also known as the Krebs cycle, is a key component of cellular respiration that occurs in the mitochondria. It processes acetyl-CoA derived from pyruvate and generates high-energy electron carriers, while releasing CO2 as a byproduct. This cycle is significant for understanding the main source of CO2 during cellular respiration.
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Acids
Glycolysis
Glycolysis is the first stage of cellular respiration, occurring in the cytoplasm, where glucose is broken down into pyruvate, producing a small amount of ATP and NADH. Importantly, glycolysis does not produce CO2; thus, it is essential to differentiate it from later stages where CO2 is released.
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Related Practice
Multiple Choice
When protein molecules are used as fuel for cellular respiration, __________ are produced as waste.
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