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Multiple Choice
Which of the following describes a frameshift mutation?
A
Insertion or deletion of nucleotides that alters the reading frame of the genetic sequence
B
Inversion of a segment of DNA
C
Substitution of one nucleotide for another without changing the reading frame
D
Duplication of a segment of DNA
Verified step by step guidance
1
Understand the concept of a frameshift mutation: A frameshift mutation occurs when nucleotides are inserted or deleted from a DNA sequence, causing a shift in the reading frame of the genetic code.
Recognize the impact of frameshift mutations: These mutations can lead to significant changes in the protein produced, as the sequence of amino acids is altered from the point of mutation onward.
Differentiate frameshift mutations from other types: Inversion, substitution, and duplication do not alter the reading frame. Inversion reverses a segment, substitution replaces one nucleotide, and duplication repeats a segment.
Identify the correct description: The insertion or deletion of nucleotides that alters the reading frame is the defining characteristic of a frameshift mutation.
Apply this understanding to the options given: The correct answer is the option that describes the insertion or deletion of nucleotides altering the reading frame.