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Multiple Choice
During depolarization of a neuron, what happens to the membrane potential?
A
The inside of the neuron's membrane becomes less negative relative to the outside.
B
There is no change in the membrane potential.
C
The membrane potential becomes zero and remains constant.
D
The inside of the neuron's membrane becomes more negative relative to the outside.
Verified step by step guidance
1
Understand the concept of depolarization: Depolarization is a process in which the membrane potential of a neuron becomes less negative (closer to zero) compared to its resting state. This occurs when positively charged ions, such as sodium (Na⁺), flow into the neuron.
Recall the resting membrane potential: At rest, the inside of a neuron is more negative relative to the outside, typically around -70 mV. This is maintained by the sodium-potassium pump and ion channels.
Identify the role of ion channels during depolarization: During depolarization, voltage-gated sodium channels open, allowing Na⁺ ions to rush into the cell. This influx of positive ions reduces the negativity inside the neuron.
Compare the membrane potential changes: As Na⁺ ions enter the neuron, the inside of the membrane becomes less negative relative to the outside. The membrane potential moves closer to zero but does not necessarily reach zero during depolarization.
Eliminate incorrect options: Based on the explanation, the correct answer is that the inside of the neuron's membrane becomes less negative relative to the outside. The other options do not accurately describe the changes in membrane potential during depolarization.