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Multiple Choice
Which organelle is primarily responsible for breaking down very-long-chain fatty acids via beta-oxidation in eukaryotic cells?
A
Lysosome
B
Rough endoplasmic reticulum
C
Peroxisome
D
Golgi apparatus
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Verified step by step guidance
1
Understand the process of beta-oxidation, which is the metabolic pathway that breaks down fatty acids to generate acetyl-CoA units.
Recall that beta-oxidation of very-long-chain fatty acids (VLCFAs) requires a specialized organelle because these fatty acids are too long to be processed efficiently in mitochondria.
Identify the organelle known for handling the initial breakdown of VLCFAs through beta-oxidation, which also contains enzymes that produce and degrade hydrogen peroxide (H2O2).
Recognize that peroxisomes are the organelles responsible for this function, as they contain the necessary enzymes for beta-oxidation of VLCFAs and detoxification of reactive oxygen species.
Eliminate other options: lysosomes degrade macromolecules via hydrolysis, rough ER is involved in protein synthesis, and Golgi apparatus modifies and sorts proteins and lipids.